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英语翻译The classⅡrelease factor,in complex with GDP ,also binds
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英语翻译
The classⅡrelease factor,in complex with GDP ,also binds the large subunit .In prokaryotes,RF3 is the classⅡrelease factor.In eukaryotes ,eRF3 in the classⅡ release factor.After the class Ⅰand classⅡrelease factors are both bound,a glycine-glycine-glutamine,or GGQ ,motif on the class Ⅰ release factor triggers hydrolysis of the protein from tRNA in the P site.
Release of the protein from the ribosome triggers the recycling of the release factors.First,GTP is exchanged for GDP on the classⅡ release factor.This cause the classⅡ release factor to push the classⅠ release factor off the ribsome.优质解答
大致意思：第II类释放因子与GDP形成的复合物与大亚基结合.在原核生物中,RF3属于第II类释放因子.在真核生物中,eRF3属于第II类释放因子.当第I类和第II类释放因子都被结合后,甘氨酸-甘氨酸-谷氨酰胺（GGQ）信号促使第I类释放因子将来自tRNA P位点的蛋白水解掉.
核糖体上蛋白质的释放触发释放因子的再循环.首先GDP被GTP从第II类释放因子上替换掉,这将导致第II类释放因子将第I类释放因子从核糖体上释放出来.
The classⅡrelease factor,in complex with GDP ,also binds the large subunit .In prokaryotes,RF3 is the classⅡrelease factor.In eukaryotes ,eRF3 in the classⅡ release factor.After the class Ⅰand classⅡrelease factors are both bound,a glycine-glycine-glutamine,or GGQ ,motif on the class Ⅰ release factor triggers hydrolysis of the protein from tRNA in the P site.
Release of the protein from the ribosome triggers the recycling of the release factors.First,GTP is exchanged for GDP on the classⅡ release factor.This cause the classⅡ release factor to push the classⅠ release factor off the ribsome.
优质解答
核糖体上蛋白质的释放触发释放因子的再循环.首先GDP被GTP从第II类释放因子上替换掉,这将导致第II类释放因子将第I类释放因子从核糖体上释放出来.
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